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Preclinical stress research: where are we headed? An early career investigator's perspective

MPG-Autoren
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Kos,  Aron
Dept. Stress Neurobiology and Neurogenetics, Max Planck Institute of Psychiatry, Max Planck Society;

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Lopez,  Juan Pablo
Dept. Stress Neurobiology and Neurogenetics, Max Planck Institute of Psychiatry, Max Planck Society;

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Zitation

Gururajan, A., Kos, A., & Lopez, J. P. (2018). Preclinical stress research: where are we headed? An early career investigator's perspective. STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS, 21(5), 384-388. doi:10.1080/10253890.2018.1446519.


Zitierlink: https://hdl.handle.net/21.11116/0000-0003-674C-5
Zusammenfassung
Stress is a major risk factor in the development of various psychiatric disorders such as depression, anxiety and post-traumatic stress disorder. The use of stress paradigms in preclinical contexts is essential to advance our understanding of the pathophysiology of these disorders. However, they are not without their limitations and in this commentary, we have examined some of the practical issues associated with their use. We also highlight some of the latest techniques to identify their neuromolecular correlates as well as the potentially important and integrative role of computational neuroscience. Finally, we share our perspective on future directions in the field of preclinical stress research.