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Book Chapter

Evolutionary perspectives on the human Gut Microbiome

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Doms,  Shauni
Guest Group Evolutionary Genomics, Max Planck Institute for Evolutionary Biology, Max Planck Society;

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Hermes,  Britt-Marie
Guest Group Evolutionary Genomics, Max Planck Institute for Evolutionary Biology, Max Planck Society;

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Baines,  John F.
Guest Group Evolutionary Genomics, Max Planck Institute for Evolutionary Biology, Max Planck Society;

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Citation

Doms, S., Hermes, B.-M., & Baines, J. F. (2018). Evolutionary perspectives on the human Gut Microbiome. In D. Haller (Ed.), The Gut Microbiome in Health and Disease (pp. 65-78). Heidelberg: Springer. doi:10.1007/978-3-319-90545-7_5.


Cite as: http://hdl.handle.net/21.11116/0000-0003-751D-A
Abstract
The renewed interest in human gut microbiome research spawned by modern developments in metagenomics resulted in many fascinating new results, but confusion and seeming contradictions are still common in this nascent field. As for other subdisciplines of biology, evolutionary biology serves as a unifying principle in studying host-microbe interactions. However, the range of perspectives offered by evolution is often not considered or fully appreciated in human gut microbiome research. In this chapter we provide a broad overview of evolutionary perspectives on the human gut microbiome, which range from the origin of holobionts to strain-level microbial variation within a host’s lifetime.