Water Diffusion and Magnetization Transfer in Normal and Pathologic Lumbar Disc

Garcia, M; Egelhof, T; Scheffler, K; Bieri, O

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Water Diffusion and Magnetization Transfer in Normal and Pathologic Lumbar Disc

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https://cds.ismrm.org/ismrm-2008/files/1_program.pdf
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Garcia, M., Egelhof, T., Scheffler, K., & Bieri, O. (2008). Water Diffusion and Magnetization Transfer in Normal and Pathologic Lumbar Disc. Poster presented at 16th Scientific Meeting and Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2008), Toronto, Canada.

Cite as: https://hdl.handle.net/21.11116/0000-0003-933B-5

Abstract

Diffusion has been shown to be sensitive to intervertebral disc degeneration and pathologies but quantification is often hampered by global motion and
susceptibilities. In this work, we investigate possible correlations between the magnetization transfer ratio (MTR) imaging and apparent diffusion constamts
(ADC) to yield a possible alternative characterization method of disc diseases that relate to diffusion. ADC and MTR is compared between normal appearing
discs of young healthy volunteers and patients. High correlations between MTR and ADC values were found suggesting that changes in water diffusion for intervertebral discs are also reflected in MT measurements.