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Meeting Abstract

Ultra high field BOLD measurements combined with simultaneous determination of blood oxygenation and blood volume by optical imaging

MPS-Authors
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Bernard,  R
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons84187

Scheffler,  K
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons84145

Pohmann,  R
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

External Resource

http://indexsmart.mirasmart.com/ISMRM2019/PDFfiles/0205.html
(Abstract)

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Citation

Bernard, R., Scheffler, K., & Pohmann, R. (2019). Ultra high field BOLD measurements combined with simultaneous determination of blood oxygenation and blood volume by optical imaging. In ISMRM 27th Annual Meeting & Exhibition.


Cite as: https://hdl.handle.net/21.11116/0000-0003-96C1-9
Abstract
To disentangle the different parameters contributing to the BOLD effect, a combined setup for intrinsic optical imaging and ultra high field fMRI in rats was designed, using a magnetic field compatible, high sensitivity camera and professional optical components. By illumination of the brain surface with light in four different wavelengths, oxygenation and CBV was observed concurrently with fMRI during forepaw stimulation. Simultaneous measurement of those parameters can help to better understand the BOLD effect and to add additional value to both optical imaging and fMRI experiments.