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Artifacts in dynamic CEST MRI due to motion and field shifts – implications for glucoCEST MRI at 3T

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Zaiss,  M
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Herz,  K
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Deshmane,  A
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Scheffler,  K
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Zaiss, M., Herz, K., Deshmane, A., Kim, M., Golay, X., Lindig, T., et al. (2019). Artifacts in dynamic CEST MRI due to motion and field shifts – implications for glucoCEST MRI at 3T. Poster presented at 27th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2019), Montréal, QC, Canada.


Cite as: https://hdl.handle.net/21.11116/0000-0003-96D2-6
Abstract
Dynamic glucose enhanced imaging yields expected CEST effects that are rather small in tissue especially at clinical field strengths (<2 %). Small movements during the dynamic CEST measurement together with a subtraction-based evaluation can lead to pseudo CEST effects of the same order of magnitude. We studied these effects by virtual difference images of a basline scan that were altered by the rigid body transformations and B0 shifts. Minor motion (0.6 mm translations) and B0 artifacts (7 Hz shift) can lead to pseudo effects in the order of 1% in dynamic CEST imaging, despite no glucose was injected at all.