Homogenous Excitation in Whole Brain CEST: Combination of Snapshot CEST and 
Multiple Interleaved Mode Saturation

Liebert, A; Zaiss, M; Gumbrecht, R; Liebig, P; Schmitt, B; Laun, F; Doerfler, A; Uder, M; Nagel, A

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Homogenous Excitation in Whole Brain CEST: Combination of Snapshot CEST and Multiple Interleaved Mode Saturation

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Zaiss, M
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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http://indexsmart.mirasmart.com/ISMRM2019/PDFfiles/0144.html
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Citation

Liebert, A., Zaiss, M., Gumbrecht, R., Liebig, P., Schmitt, B., Laun, F., et al. (2019). Homogenous Excitation in Whole Brain CEST: Combination of Snapshot CEST and Multiple Interleaved Mode Saturation. Poster presented at 27th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2019), Montréal, QC, Canada.

Cite as: https://hdl.handle.net/21.11116/0000-0003-96DD-B

Abstract

To perform Chemical Exchange Saturation Transfer MRI of the whole brain a homogeneous saturation and fast readout are required. To achieve a fast and robust 3D acquisition a spiral-centric-reordered GRE readout was used. In addition, a Multiple Interleaved Mode Saturation scheme was applied to mitigate B1+-inhomogeneity effects of the CEST saturation. Combination of these two methods allows acquiring a homogenous CEST contrast in a volume of approximately 220x220x45mm3 within an acquisition time of 7 min 26s.