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Development of whole-brain 3D snapshot CEST MRI at 3T

MPS-Authors
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Mueller,  S
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Deshmane,  A
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Herz,  K
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons84187

Scheffler,  K
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Zaiss,  M
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Mueller, S., Deshmane, A., Herz, K., Scheffler, K., & Zaiss, M. (2019). Development of whole-brain 3D snapshot CEST MRI at 3T. Poster presented at 27th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2019), Montréal, QC, Canada.


Cite as: https://hdl.handle.net/21.11116/0000-0003-9705-D
Abstract
In its application Chemical exchange saturation transfer (CEST) suffers from the drawback of long acquisition times. To approach this issue we demonstrate the feasibility of a 3D gradient echo based CEST sequence for 3T that provides whole brain (WB) coverage without additional measurement time. In addition, the suggested post processing helps to improve the determination of the CEST effects from the WB data. CEST contrasts derived from the presented method are of equal quality as those of commonly used methods.