The Neurotransmitter NAAG in Different Phases of Relapsing-Remitting Multiple 
Sclerosis Patients

Wyss, PO; Pfender, N; Martin, R; Lutterotti, A; Henning, A

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The Neurotransmitter NAAG in Different Phases of Relapsing-Remitting Multiple Sclerosis Patients

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Wyss, PO
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Henning, A
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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引用

Wyss, P., Pfender, N., Martin, R., Lutterotti, A., & Henning, A. (2019). The Neurotransmitter NAAG in Different Phases of Relapsing-Remitting Multiple Sclerosis Patients. Poster presented at 27th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2019), Montréal, QC, Canada.

引用: https://hdl.handle.net/21.11116/0000-0003-9CF9-5

要旨

This study explores the alterations of N-Acetyl aspartate (NAA) and the neurotransmitter N-Acetyl aspartyl glutamate (NAAG) in the cerebral normal-appearing white tissue of multiple sclerosis patients with a relapsing-remitting course. A two-dimensional J-resolved single voxel spectroscopy sequence and two-dimensional prior-knowledge fitting is used to disentangle the resonance lines of NAA and NAAG.