Longitudinal Relaxation Times of Metabolites in vivo at 9.4 T

Wright, A; Murali-Manohar, S; Borbath, T; Henning, A

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Longitudinal Relaxation Times of Metabolites in vivo at 9.4 T

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Wright, A
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Murali-Manohar, S
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Borbath, T
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Henning, A
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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引用

Wright, A., Murali-Manohar, S., Borbath, T., & Henning, A. (2019). Longitudinal Relaxation Times of Metabolites in vivo at 9.4 T. In ISMRM 27th Annual Meeting & Exhibition.

引用: https://hdl.handle.net/21.11116/0000-0003-9D21-7

要旨

Longitudinal relaxation times for 11 human brain metabolites are reported for GM and WM rich voxels at 9.4T. These values are reported to potentiate the ability to perform absolute quantification at 9.4T in humans with reference to water. A bi-exponential model was used to fit the signal curve from using an inversion recovery metabolite cycling STEAM sequence. Results are further extrapolated to report the T1-relaxation from a theoretically pure WM and GM voxel by means of a linear assumption of the relaxation time and tissue contribution of a voxel.