Cytochalasin D is able to mimic the effects of phalloidin on the rat liver

Jahn, Werner

doi:10.1007/BF01953240

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Cytochalasin D is able to mimic the effects of phalloidin on the rat liver

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Jahn, Werner
Muscle Research, Max Planck Institute for Medical Research, Max Planck Society;

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Jahn, W. (1979). Cytochalasin D is able to mimic the effects of phalloidin on the rat liver. Experientia: interdisciplinary journal for the life sciences, 35(12), 1638-1639. doi:10.1007/BF01953240.

Cite as: https://hdl.handle.net/21.11116/0000-0003-9DBB-A

Abstract

Cytochalasin D induces a strong potassium release in the isolated perfused rat liver and leads to vacuolization of the liver parenchymal cells. These effects are similar to the action of phalloidin on the rat liver. Since phalloidin and cytochalasin act in a different way on microfilaments, it is suggested that any disturbance of the function of microfilaments can induce these effects.