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Meeting Abstract

Downfield Spectra at Ultrahigh Field

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Henning, A., Fuchs, A., Boesch, C., & Boesiger, P. (2008). Downfield Spectra at Ultrahigh Field. In 16th Scientific Meeting and Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2008) (pp. 150).

Cite as: https://hdl.handle.net/21.11116/0000-0003-A9FD-2
The advantages of very high fields for MRS in humans (increased SNR and chemical shift dispersion) have been exploited for the upfield part of the human
cerebral 1H spectrum but not for the downfield part, which is still poorly characterized. In this work, 7T downfield spectra from human periventricular white
matter are presented, compared to corresponding spectra recorded at lower field strength and characterized regarding contributing metabolites and relaxation
behaviour as well as in view of chemical exchange with (suppressed) water. Communalities, but also substantial differences were found when compared to
equivalent spectra obtained at lower fields.