Sensitivity Encoded VAPOR-FIDLOVS at 7T: Mapping the Hidden Metabolites

Henning, A; Fuchs, A; Murdoch, J; Boesiger, P

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Meeting Abstract

Sensitivity Encoded VAPOR-FIDLOVS at 7T: Mapping the Hidden Metabolites

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Zitation

Henning, A., Fuchs, A., Murdoch, J., & Boesiger, P. (2008). Sensitivity Encoded VAPOR-FIDLOVS at 7T: Mapping the Hidden Metabolites. In 16th Scientific Meeting and Exhibition of the International Society of Magnetic Resonance in Medicine (ISMRM 2008) (pp. 111).

Zitierlink: https://hdl.handle.net/21.11116/0000-0003-AA0B-2

Zusammenfassung

For MRSI acquisition at 7T direct acquisition of the Free Induction Decay Localized by Outer Volume Suppression (FIDLOVS) is proposed to minimize
SNR loss due to short T2 relaxation times. To that, a broadband frequency-modulated excitation pulse for slice-selection and a numerically optimized outervolume-
suppression scheme, which considers T1 relaxation of skull lipid, B1 inhomogeneity, saturation band crossing and is based on broadband PPRpulses,
for in-plane localization are applied. The resulting signal-to-noise ratio (SNR) and spectral resolution enable mapping of 15 metabolites. The high
SNR is also the base for highly spatially resolved metabolite mapping accelerated by sensitivity encoding.