Enterotypes in the landscape of gut microbial community composition

Costea, PI; Hildebrand, F; Arumugam, M; Backhed, F; Blaser, MJ; Bushman, FD; de Vos, WM; Ehrlich, SD; Fraser, CM; Hattori, M; Huttenhower, C; Jeffery, IB; Knights, D; Lewis, JD; Ley, RE; Ochman, H; O'Toole, PW; Quince, C; Relman, DA; Shanahan, F; Sunagawa, S; Wang, J; Weinstock, GM; Wu, GD; Zeller, G; Zhao, L; Raes, J; Knight, R; Bork, P

doi:10.1038/s41564-017-0072-8

アイテム詳細

登録内容を編集ファイル形式で保存

一時保存へ追加

タグ情報を表示リリース履歴を表示詳細要約

公開

学術論文

Enterotypes in the landscape of gut microbial community composition

MPS-Authors

/persons/resource/persons270516

Ley, RE
Department Microbiome Science, Max Planck Institute for Developmental Biology, Max Planck Society;

External Resource

There are no locators available

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

フルテキスト (公開)

公開されているフルテキストはありません

付随資料 (公開)

There is no public supplementary material available

引用

Costea, P., Hildebrand, F., Arumugam, M., Backhed, F., Blaser, M., Bushman, F., de Vos, W., Ehrlich, S., Fraser, C., Hattori, M., Huttenhower, C., Jeffery, I., Knights, D., Lewis, J., Ley, R., Ochman, H., O'Toole, P., Quince, C., Relman, D., Shanahan, F., Sunagawa, S., Wang, J., Weinstock, G., Wu, G., Zeller, G., Zhao, L., Raes, J., Knight, R., & Bork, P. (2017). Enterotypes in the landscape of gut microbial community composition. Nature Microbiology, 3(1), 8-16. doi:10.1038/s41564-017-0072-8.

引用: https://hdl.handle.net/21.11116/0000-0003-B6AA-0

要旨

Population stratification is a useful approach for a better understanding of complex biological problems in human health and wellbeing. The proposal that such stratification applies to the human gut microbiome, in the form of distinct community composition types termed enterotypes, has been met with both excitement and controversy. In view of accumulated data and re-analyses since the original work, we revisit the concept of enterotypes, discuss different methods of dividing up the landscape of possible microbiome configurations, and put these concepts into functional, ecological and medical contexts. As enterotypes are of use in describing the gut microbial community landscape and may become relevant in clinical practice, we aim to reconcile differing views and encourage a balanced application of the concept.