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Multi-Slice LINE-scanning (MS-LINE) method to characterize the laminar specificity and variability in both evoked and resting-state fMRI

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Choi,  S
Research Group Translational Neuroimaging and Neural Control, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons214943

Zeng,  H
Research Group Translational Neuroimaging and Neural Control, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons133486

Yu,  X
Research Group Translational Neuroimaging and Neural Control, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Choi, S., Zeng, H., Biswal, B., Rosen, B., & Yu, X. (2019). Multi-Slice LINE-scanning (MS-LINE) method to characterize the laminar specificity and variability in both evoked and resting-state fMRI. Poster presented at 27th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2019), Montreal, Canada.


Cite as: https://hdl.handle.net/21.11116/0000-0003-C784-7
Abstract
Ultra-high field magnetic field strengths open new possibility for studying the neuronal input/output circuitry of the cortex and functional connectivity across the cortical layers. However, the spatiotemporal characteristics of laminar-specific fMRI signal remains to be better characterized in both task-related and resting state condition. Here, we present Multi-Slice FLASH based LINE-scanning (MS-LINE) methods, showing the multi-slice laminar-specific fMRI variability at different cortical regions of anesthetized rats. The results identify the distinct neurovascular coupling laminar patterns corresponding to different state of brain activity.