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Journal Article

Antioxidant activity of cerium dioxide nanoparticles and nanorods in scavenging hydroxyl radicals

MPS-Authors
/persons/resource/persons204194

Filippi,  Alexander
Multiphase Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

/persons/resource/persons187664

Liu,  Fobang
Multiphase Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

/persons/resource/persons230415

Wilson,  Jake
Multiphase Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

/persons/resource/persons222959

Lelieveld,  Steven
Multiphase Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

/persons/resource/persons239493

Wang,  Ting
Multiphase Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

/persons/resource/persons101189

Pöschl,  Ulrich
Multiphase Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

/persons/resource/persons192191

Tong,  Haijie
Multiphase Chemistry, Max Planck Institute for Chemistry, Max Planck Society;

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Citation

Filippi, A., Liu, F., Wilson, J., Lelieveld, S., Korschelt, K., Wang, T., et al. (2019). Antioxidant activity of cerium dioxide nanoparticles and nanorods in scavenging hydroxyl radicals. RSC Advances, 9(20), 11077-11081. doi:10.1039/c9ra00642g.


Cite as: https://hdl.handle.net/21.11116/0000-0003-EA15-E
Abstract
Cerium oxide nanoparticles (CeNPs) have been shown to exhibit antioxidant capabilities, but their efficiency in scavenging reactive oxygen species (ROS) and the underlying mechanisms are not yet well understood. In this study, cerium dioxide nanoparticles (CeNPs) and nanorods (CeNRs) were found to exhibit much stronger scavenging activity than ·OH generation in phosphate buffered saline (PBS) and surrogate lung fluid (SLF). The larger surface area and higher defect density of CeNRs may lead to higher ·OH scavenging activity than for CeNPs. These insights are important to understand the redox activity of cerium nanomaterials and provide clues to the role of CeNPs in biological and environmental processes.