English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT

Released

Meeting Abstract

Voltage Sensitive Dye Imaging of Crossmodal Interactions in Rat Neocortex

MPS-Authors
/persons/resource/persons84061

Lippert,  MT
Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

External Ressource
No external resources are shared
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available
Citation

Lippert, M. (2007). Voltage Sensitive Dye Imaging of Crossmodal Interactions in Rat Neocortex. In 8th Conference of Tuebingen Junior Neuroscientists (NeNa 2007) (pp. 13).


Cite as: http://hdl.handle.net/21.11116/0000-0003-EF8A-5
Abstract
Responses to crossmodal stimuli have been observed in a wide range of brain regions, where they have been studied in great detail. Although many crossmodal areas have been characterized, the spatiotemporal characteristics of such activity are still largely unknown. We used voltage-sensitive dye imaging (VSDI) to address this question. For the presented study, three cortical regions in rat were imaged: primary visual cortex (V1), barrel field of primary somatosensory cortex (S1bf) and parietal association area (PA, flanked by V1 and S1bf). We find that sensory-evoked population activity can propagate in the form of a distinct wave, robustly in either crossmodal direction, i.e. from S1bf to V1, or from V1 to S1bf. In single trials, the waveforms changed continuously during propagation, with dynamic variability from trial to trial, which we interpret as evidence for cortical involvement in the spreading process. We further investigated the propagation of spontaneous sleep-like waves in this area using a novel flow-detection algorithm. Results of these experiments show that spontaneous activity also tends to propagate parallel to the crossmodal axis, rather than orthogonal to it. Taken together, these findings demonstrate that cortical networks can show pre-attentive crossmodal propagation of activity, and suggest a potential mechanism for the establishment of crossmodal integration.