Diffusion Effects in Passband Balanced SSFP fMRI

Klarhöfer, M; Bieri, O; Scheffler, K

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Diffusion Effects in Passband Balanced SSFP fMRI

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https://cds.ismrm.org/ismrm-2007/files/1_program.pdf
(Abstract)

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Citation

Klarhöfer, M., Bieri, O., & Scheffler, K. (2007). Diffusion Effects in Passband Balanced SSFP fMRI. Poster presented at 2007 Joint Annual Meeting ISMRM-ESMRMB, Berlin, Germany.

Cite as: https://hdl.handle.net/21.11116/0000-0004-04EC-E

Abstract

The dependency of the balanced SSFP signal on the resonance frequency can be used to detect BOLD related frequency changes in functional MRI. Recent work demonstrates that diffusion in inhomogeneous magnetic fields affects the balanced SSFP signal amplitude. Due to this susceptibility sensitivity also the signal amplitude of an on-resonant balanced SSFP sequence depends on deoxyhemoglobin concentrations. Data from a visual fMRI study support the predicted dependency on the flip angle. However, low sensitivity or off-resonance effects prevented verification of the weaker effects of the repetition time on measured signal changes.