On Magnetization Transfer and Balanced SSFP

Bieri, O; Scheffler, K

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On Magnetization Transfer and Balanced SSFP

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https://cds.ismrm.org/ismrm-2007/files/1_program.pdf
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Bieri, O., & Scheffler, K. (2007). On Magnetization Transfer and Balanced SSFP. Poster presented at 2007 Joint Annual Meeting ISMRM-ESMRMB, Berlin, Germany.

Cite as: https://hdl.handle.net/21.11116/0000-0004-0509-D

Abstract

Balanced steady state free precession (bSSFP) suffers from a substantial signal loss in tissues due to magnetization transfer (MT). We will show that MT effects in bSSFP can be modulated by a modification of the sequence scheme. Optimized bSSFP protocol settings are derived that yield maximal sensitivity to MT while minimizing contribution from other impurities, such as off-resonances. Evaluation in human brain shows high correlation with commonly used
gradient echo sequences. In summary, a novel method to generate and quantify MT from bSSFP image acquisitions is presented and factors that optimize and influence this contrast are discussed.