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High‐resolution diffusion‐weighted imaging identifies ischemic lesions in a majority of transient ischemic attack patients

MPG-Autoren
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Villringer,  Arno
Center for Stroke Research, Charité University Medicine Berlin, Germany;
Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

Endres,  Matthias
Center for Stroke Research, Charité University Medicine Berlin, Germany;
Department of Neurology, Charité University Medicine Berlin, Germany;
Berlin Institute of Health (BIH), Germany;
Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society;
German Centre for Cardiovascular Research, Berlin, Germany;
German Center for Neurodegenerative Diseases, Berlin, Germany;

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Zitation

Hotter, B., Galinovic, I., Kunze, C., Brunecker, P., Jungehulsing, G. J., Villringer, A., et al. (2019). High‐resolution diffusion‐weighted imaging identifies ischemic lesions in a majority of transient ischemic attack patients. Annals of Neurology, 86(3), 452-457. doi:10.1002/ana.25551.


Zitierlink: https://hdl.handle.net/21.11116/0000-0004-9276-2
Zusammenfassung
Transient ischemic attack (TIA) is defined as focal neurological deficit caused by ischemia resolving within 24 hours. In a secondary analysis of a large monocentric cohort of 446 TIA patients, we explored the frequency and determinants of diffusion-weighted imaging (DWI) lesions on high-resolution magnetic resonance imaging. Overall, 240 (54%) of all TIA patients presented with DWI lesions. These patients had higher National Institute of Health Stroke Scale and ABCD2 scores and presented more frequently with vessel occlusion and perfusion deficits, but had similar functional outcome at 3 months. Taken together, high-resolution DWI provides evidence of ischemic brain injury in the majority of TIA patients.