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Poster

Localization analysis of TMS effects during motor cortex stimulation

MPS-Authors
/persons/resource/persons212471

Weise,  Konstantin
Methods and Development Unit - MEG and Cortical Networks, MPI for Human Cognitive and Brain Sciences, Max Planck Society;
Technische Universität Ilmenau;

/persons/resource/persons209297

Numssen,  Ole
Lise Meitner Research Group Cognition and Plasticity, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

Thielscher,  A.
Former Department MRZ, Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons185449

Hartwigsen,  Gesa
Lise Meitner Research Group Cognition and Plasticity, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

/persons/resource/persons19779

Knösche,  Thomas R.
Methods and Development Unit - MEG and Cortical Networks, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Citation

Weise, K., Numssen, O., Thielscher, A., Hartwigsen, G., & Knösche, T. R. (2018). Localization analysis of TMS effects during motor cortex stimulation. Poster presented at 24th Annual Meeting of the Organization for Human Brain Mapping (OHBM), Singapore.


Cite as: https://hdl.handle.net/21.11116/0000-0004-A97F-0
Abstract
Transcranial magnetic stimulation (TMS)
allows for non-invasive electromagnetic
stimulation of the cortex. However, its
exact neurophysiological mechanisms
remain elusive, leading to considerable
variation in observed effects [1].
Depending on stimulation intensity and
target, the stimulation can directly lead
to observable effects, such as motor re-
sponses. Although head modeling allows
for a prediction of the induced electric
field in the head [2], the stimulated
areas may be extended and do not uni-
quely identify the location of the effect
cause.
Here, we present a novel method that
employs biophysical forward modeling
(Fig. 2) and stimulation with variable coil
positions and orientations, in order to
exactly localize the neural populations
that are causally linked to motor evoked
potentials (MEP).