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Poster

The influence of draining veins on apparent grey matter volume changes caused by hypercapnia

MPS-Authors
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Steele,  Christopher
Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Jäger,  Anna-Thekla
Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Tardif,  Christine
Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Villringer,  Arno
Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Bazin,  Pierre-Louis
Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Gauthier,  Claudine
Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Citation

Huck, J., Steele, C., Jäger, A.-T., Fan, A., Grahl, S., Tardif, C., et al. (2019). The influence of draining veins on apparent grey matter volume changes caused by hypercapnia. Poster presented at ISMRM 27th Annual Meeting and Exhibition, Montreal, QC, Canada.


Cite as: https://hdl.handle.net/21.11116/0000-0004-CFD7-1
Abstract
Past studies have shown that T1-weighted measures of grey matter volume (GMV) can be biased by differences in blood volume. Here, we investigate the vascular compartments associated with this bias by quantifying the spatial relationship between t-values for the apparent GMV increase observed during hypercapnia and the location of draining veins. Draining veins were identified using the VENAT atlas. Overall, the results of this analysis demonstrate that while proximity to veins is related to the presence of higher t-values (larger apparent GMV change during hypercapnia), large veins themselves are unlikely to be the main cause of this bias; suggesting that smaller veins or arteries may have a larger role in the observed bias.