Isolation and amino acid sequence of a morphogenetic peptide from hydra

Schaller, H. Chica; Bodenmüller, Heinz

doi:10.1073/pnas.78.11.7000

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Isolation and amino acid sequence of a morphogenetic peptide from hydra

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Schaller, H. Chica
Max Planck Institute for Medical Research, Max Planck Society;

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Bodenmüller, Heinz
Max Planck Institute for Medical Research, Max Planck Society;

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Citation

Schaller, H. C., & Bodenmüller, H. (1981). Isolation and amino acid sequence of a morphogenetic peptide from hydra. Proceedings of the National Academy of Sciences of the United States of America, 78(11), 7000-7004. doi:10.1073/pnas.78.11.7000.

Cite as: https://hdl.handle.net/21.11116/0000-0004-EBBA-2

Abstract

From Anthopleura elegantissima and from Hydra attenuata, a morphogenetic peptide-the head activator-was isolated in pure form. The sequence of the head activator was established by enzymatic and by chemical degradation of the whole peptide or fragments thereof and subsequent analysis of the amino acids by micromethods. The head activator from both sources was identical and has the sequence:<pGlu-Pro-Pro-Gly-Gly-Ser-Lys-Val-Ile-Leu-Phe.