Facile access to chiral non-natural amino acids

Planas, Oriol; Cornella, Josep

doi:10.1038/s41929-019-0367-7

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Facile access to chiral non-natural amino acids

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Planas, Oriol
Research Group Cornellà, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

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Cornella, Josep
Research Group Cornellà, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

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Citation

Planas, O., & Cornella, J. (2019). Facile access to chiral non-natural amino acids. Nature Catalysis, 2(10), 839-840. doi:10.1038/s41929-019-0367-7.

Cite as: https://hdl.handle.net/21.11116/0000-0004-F0D3-E

Abstract

Given the importance of enantioenriched β²- and β³-amino acids as building blocks, direct and versatile methods for their synthesis are highly coveted by organic chemists. Now, using easily accessible 1,3-oxazinane motifs, a regiodivergent and enantioselective C–H functionalization method permits their synthesis in a straightforward and practical fashion.