Current Source Density Analysis of Spatio-Temporal Fluorescence Maps in 
Organotypical Slice Cultures

Plenz, D; Aertsen, A

doi:10.1007/978-3-642-49967-8_17

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Current Source Density Analysis of Spatio-Temporal Fluorescence Maps in Organotypical Slice Cultures

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Plenz, D
Former Department Structure and Function of Natural Nerve-Net , Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Aertsen, A
Former Department Structure and Function of Natural Nerve-Net , Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Plenz, D., & Aertsen, A. (1992). Current Source Density Analysis of Spatio-Temporal Fluorescence Maps in Organotypical Slice Cultures. In A. Aertsen, & V. Braitenberg (Eds.), Information Processing in the Cortex: Experiments and Theory (pp. 253-269). Berlin, Germany: Springer.

Cite as: https://hdl.handle.net/21.11116/0000-0005-0C63-F

Abstract

Spatio-temporal spreading of activity in the CA3 region of organotypical slice cultures from the rat hippocampus was studied by measuring the intracellular potential distributions, using the optical recording technique. To enhance the spatial resolution, a specifically developed CSD-like transformation was applied to the fluorescence maps, enabling to calculate the locations of the transmembrane current generators (iCSD).