Compartmental Balloon and BOLD Model

Uludag, K; Buxton, RB

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Meeting Abstract

Compartmental Balloon and BOLD Model

MPS-Authors

/persons/resource/persons84269

Uludag, K
Former Department MRZ, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

External Resource

https://cds.ismrm.org/ismrm-2005/Files/00024.pdf
(Any fulltext)

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Uludag, K., & Buxton, R. (2005). Compartmental Balloon and BOLD Model. In 13th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2005).

Cite as: https://hdl.handle.net/21.11116/0000-0005-41D6-0

Abstract

The BOLD effect in response to activation is sensitive to the concentration change of deoxy-Hb, which in turn is dependent on CBF, CBV and CMRO2. To relate these quantities, Buxton et al. proposed a balloon model based on the distensibility of the venous vessels. Here, we develop an extension to the current model in modelling the dynamics of deoxy-Hb and CBV not only in the venous part but in all vascular compartments and their individual intra- and extravascular contributions to the BOLD effect. Thus, the new model can predict outcomes of high-resolution imaging and solve apparent contradictions in experimental data.