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Single-shot dual-echo EPI detects functional activation of the cerebellum during duration working memory task

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Mathiak, K., Hertrich, I., Weiskopf, N., Grodd, W., & Ackermann, A. (2003). Single-shot dual-echo EPI detects functional activation of the cerebellum during duration working memory task. Poster presented at 11th Scientific Meeting of the International Society of Magnetic Resonance in Medicine (ISMRM 2003), Toronto, ON, Canada.


Cite as: http://hdl.handle.net/21.11116/0000-0005-816E-E
Abstract
The cerebellum was suggested to subserve cognitive function by timing operations. In order to conduct a functional imaging study of the basal brain structures, we applied single-shot dual-echo echo planar imaging (EPI). As compared to conventional EPI, image distortion and acquisition time (TA = 1.8 sec / 28 slices) were reduced without deteriorating the contrast-to-noise ratio (CNR). Using TE = 28 and 66 ms at 1.5 T, echoes were combined for locally optimal T2*-weighted CNR. Right Crus I of the cerebellum exhibited increased signal selectively to working memory operations on auditory pause durations (30 140 ms) independent of stimulus parameters.