English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT

Released

Journal Article

Nitroxide derivatives for dynamic nuclear polarization in liquids: The role of rotational diffusion.

MPS-Authors
/persons/resource/persons238452

Levien,  M.
Research Group of Electron Paramagnetic Resonance, MPI for Biophysical Chemistry, Max Planck Society;

/persons/resource/persons232625

Hiller,  M.
Research Group of Electron Paramagnetic Resonance, MPI for Biophysical Chemistry, Max Planck Society;

/persons/resource/persons15928

Tkach,  I.
Research Group of Electron Paramagnetic Resonance, MPI for Biophysical Chemistry, Max Planck Society;

/persons/resource/persons14834

Bennati,  M.
Research Group of Electron Paramagnetic Resonance, MPI for Biophysical Chemistry, Max Planck Society;

/persons/resource/persons194882

Orlando,  T.
Research Group of Electron Paramagnetic Resonance, MPI for Biophysical Chemistry, Max Planck Society;

External Ressource
No external resources are shared
Fulltext (public)

3191322.pdf
(Publisher version), 2MB

Supplementary Material (public)

3191322-Suppl.pdf
(Supplementary material), 6MB

Citation

Levien, M., Hiller, M., Tkach, I., Bennati, M., & Orlando, T. (2020). Nitroxide derivatives for dynamic nuclear polarization in liquids: The role of rotational diffusion. The Journal of Physical Chemistry Letters, 11(5), 1629-1635. doi:10.1021/acs.jpclett.0c00270.


Cite as: http://hdl.handle.net/21.11116/0000-0005-9999-2
Abstract
Polarization transfer efficiency in liquid-state dynamic nuclear polarization (DNP) depends on the interaction between polarizing agents (PAs) and target nuclei modulated by molecular motions. Hereby, we show how translational and rotational diffusion differently affect the DNP efficiency. These contributions were disentangled by measuring 1H-DNP enhancements of toluene and chloroform doped with nitroxide derivatives at 0.34 T as a function of either the temperature or the size of the PA. The results were employed to analyse 13C-DNP data at higher fields, where the polarization transfer is also driven by the Fermi contact interaction. In this case, bulky nitroxide PAs perform better than the small TEMPONE radical due to structural fluctuations of the ring conformation. These findings will help in designing PAs with features specifically optimized for liquid state DNP at various fields.