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Dual Ligand-Enabled Nondirected C-H Cyanation of Arenes

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Chen,  Hao
Research Department Schlögl, Max Planck Institute for Chemical Energy Conversion, Max Planck Society;

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Mondal,  Arup
Research Department Schlögl, Max Planck Institute for Chemical Energy Conversion, Max Planck Society;

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Wedi,  Philipp
Research Department Schlögl, Max Planck Institute for Chemical Energy Conversion, Max Planck Society;

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van Gemmeren,  Manuel
Research Department Schlögl, Max Planck Institute for Chemical Energy Conversion, Max Planck Society;

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Citation

Chen, H., Mondal, A., Wedi, P., & van Gemmeren, M. (2019). Dual Ligand-Enabled Nondirected C-H Cyanation of Arenes. ACS Catalysis, 9(3), 1979-1984. doi:10.1021/acscatal.8b04639.


Cite as: https://hdl.handle.net/21.11116/0000-0005-A9F9-4
Abstract
Aromatic nitriles are key structural units in organic chemistry and, therefore, highly attractive targets for C-H activation. Herein, the development of an arene-limited, nondirected C-H cyanation based on the use of two cooperatively acting commercially available ligands is reported. The reaction enables the cyanation of arenes by C-H activation in the absence of directing groups and is therefore complementary to established approaches.