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Journal Article

Appetite for Arginine: Metabolic Control of Macrophage Hunger

MPS-Authors
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Puleston,  Daniel
Department Immunometabolism, Max Planck Institute of Immunobiology and Epigenetics, Max Planck Society;

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Pearce,  Erika L.
Department Immunometabolism, Max Planck Institute of Immunobiology and Epigenetics, Max Planck Society;

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Appetite for arginine.pdf
(Publisher version), 353KB

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Citation

Puleston, D., & Pearce, E. L. (2020). Appetite for Arginine: Metabolic Control of Macrophage Hunger. Cell Metabolism, 31, 441-442. doi:10.1016/j.cmet.2020.02.005.


Cite as: http://hdl.handle.net/21.11116/0000-0006-3B82-5
Abstract
Engulfment of dying cells by phagocytes is essential to maintain tissue function and promote injury resolution and repair. This process, termed efferocytosis, requires persistent corpse engulfment and remains a poorly understood mechanism. Here, we preview findings from Yurdagul et al. (2020) that detail how continual efferocytosis is supported by metabolites derived from the dying cell itself.