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Journal Article

The Importance of methionine metabolism

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Klein-Geltink,  Ramon
Department Immunometabolism, Max Planck Institute of Immunobiology and Epigenetics, Max Planck Society;

Pearce ,  Erika L.
Department Immunometabolism, Max Planck Institute of Immunobiology and Epigenetics, Max Planck Society;

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Klein-Geltink, R., & Pearce, E. L. (2019). The Importance of methionine metabolism. eLife, 8, e47221. doi:10.7554/eLife.47221.


Cite as: http://hdl.handle.net/21.11116/0000-0006-3F3B-3
Abstract
T helper cells import the amino acid methionine to synthesize new proteins and to provide the methyl groups needed for the methylation of RNA and DNA that drives T cell proliferation and differentiation.