English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
Add to Basket
  Local TagsRelease HistoryDetailsSummary

Released
Book Chapter

Proteins and Nucleotide Sequences Involved in DNA Replication of Filamentous Bacteriophage

MPS-Authors
/persons/resource/persons93045

Geider,  Klaus
Emeritus Group Biophysics, Max Planck Institute for Medical Research, Max Planck Society;

/persons/resource/persons82047

Meyer,  Thomas F.
Department of Molecular Biology, Max Planck Institute for Infection Biology, Max Planck Society;

/persons/resource/persons242059

Bäumel,  Irmtraud
Max Planck Institute for Medical Research, Max Planck Society;

/persons/resource/persons242089

Reimann,  A.
Max Planck Institute for Medical Research, Max Planck Society;

External Resource

https://link.springer.com/content/pdf/10.1007%2F978-1-4684-8730-5_4.pdf
(Any fulltext)

https://doi.org/10.1007/978-1-4684-8730-5_4
(Any fulltext)

Fulltext (restricted access)
There are currently no full texts shared for your IP range.
Fulltext (public)
There are no public fulltexts stored in PuRe
Supplementary Material (public)
There is no public supplementary material available
Citation

Geider, K., Meyer, T. F., Bäumel, I., & Reimann, A. (1984). Proteins and Nucleotide Sequences Involved in DNA Replication of Filamentous Bacteriophage. In U. Hübscher, & S. Spadari (Eds.), Proteins Involved in DNA Replication (pp. 45-54). Boston, MA: Springer.


Cite as: https://hdl.handle.net/21.11116/0000-0006-6ED4-0
Abstract
Filamentous bacteriophages (fd, M13, f1) contain single-stranded circular DNA of about 6400 bases (1). They penetrate the host cell via pili induced by the F-episome of an Escherichia coli cell. During the penetration process their single-stranded genome is converted into double-stranded DNA which is the main viral component in the first minutes after infection. Later in the life cycle, viral single strands are formed and complexed with gene 5 protein. They are assembled in the host membrane into phage particles, which penetrate the cell wall without severe damage of the host. Filamentous phages are quite flexible on the size of the DNA to be packaged. They spontaneously generate miniphages of about 1 kb (2, 3), but they can also comprise artificial DNA sequences up to a length of 15 kb, if the phage packaging signal is provided (4).