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Journal Article

Content-aware image restoration for electron microscopy.

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Krull,  Alexander
Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society;

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Pigino,  Gaia
Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society;

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Jug,  Florian
Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society;

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Citation

Buchholz, T.-O., Krull, A., Shahidi, R., Pigino, G., Jékely, G., & Jug, F. (2019). Content-aware image restoration for electron microscopy. Methods in cell biology, 152, 277-289. doi:10.1016/bs.mcb.2019.05.001.


Cite as: https://hdl.handle.net/21.11116/0000-0006-7D62-0
Abstract
Multiple approaches to use deep neural networks for image restoration have recently been proposed. Training such networks requires well registered pairs of high and low-quality images. While this is easily achievable for many imaging modalities, e.g., fluorescence light microscopy, for others it is not. Here we summarize on a number of recent developments in the fast-paced field of Content-Aware Image Restoration (CARE), in particular, and the associated area of neural network training, more in general. We then give specific examples how electron microscopy data can benefit from these new technologies.