Tick-tock hedgehog-mutual crosstalk with liver circadian clock promotes liver 
steatosis.

Marbach-Breitrück, Eugenia; Matz-Soja, Madlen; Abraham, Ute; Schmidt-Heck, Wolfgang; Sales, Susanne; Rennert, Christiane; Kern, Matthias; Aleithe, Susanne; Spormann, Luise; Thiel, Carlo; Gerlini, Raffaele; Arnold, Katrin; Klöting, Nora; Guthke, Reinhard; Rozman, Damjana; Teperino, Raffaele; Shevchenko, Andrej; Kramer, Achim; Gebhardt, Rolf

doi:10.1016/j.jhep.2019.01.022

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

Tick-tock hedgehog-mutual crosstalk with liver circadian clock promotes liver steatosis.

MPS-Authors

/cone/persons/resource/persons219612

Sales, Susanne
Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society;

/cone/persons/resource/persons218972

Shevchenko, Andrej
Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society;

External Resource

No external resources are shared

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

There are no public fulltexts stored in PuRe

Supplementary Material (public)

There is no public supplementary material available

Citation

Marbach-Breitrück, E., Matz-Soja, M., Abraham, U., Schmidt-Heck, W., Sales, S., Rennert, C., et al. (2019). Tick-tock hedgehog-mutual crosstalk with liver circadian clock promotes liver steatosis. Journal of hepatology, 70(6), 1192-1202. doi:10.1016/j.jhep.2019.01.022.

Cite as: https://hdl.handle.net/21.11116/0000-0006-7E68-9

Abstract

The mammalian circadian clock controls various aspects of liver metabolism and integrates nutritional signals. Recently, we described Hedgehog (Hh) signaling as a novel regulator of liver lipid metabolism. Herein, we investigated crosstalk between hepatic Hh signaling and circadian rhythm.