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Unbiased Screens for Modifiers of Alpha-Synuclein Toxicity.

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Bickle,  Marc
Max Planck Institute for Molecular Cell Biology and Genetics, Max Planck Society;

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Citation

Höllerhage, M., Bickle, M., & Höglinger, G. U. (2019). Unbiased Screens for Modifiers of Alpha-Synuclein Toxicity. Current neurology and neuroscience reports, 19(2): 8. doi:10.1007/s11910-019-0925-z.


Cite as: https://hdl.handle.net/21.11116/0000-0006-7E76-9
Abstract
We provide an overview about unbiased screens to identify modifiers of alpha-synuclein (αSyn)-induced toxicity, present the models and the libraries that have been used for screening, and describe how hits from primary screens were selected and validated.