English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT

Released

Journal Article

Synthetic cell division via membrane-transforming molecular assemblies

MPS-Authors
/persons/resource/persons145387

Kretschmer,  Simon
Schwille, Petra / Cellular and Molecular Biophysics, Max Planck Institute of Biochemistry, Max Planck Society;

/persons/resource/persons192369

Ganzinger,  Kristina
Schwille, Petra / Cellular and Molecular Biophysics, Max Planck Institute of Biochemistry, Max Planck Society;

/persons/resource/persons127954

Franquelim,  Henri
Schwille, Petra / Cellular and Molecular Biophysics, Max Planck Institute of Biochemistry, Max Planck Society;

/persons/resource/persons15815

Schwille,  Petra
Schwille, Petra / Cellular and Molecular Biophysics, Max Planck Institute of Biochemistry, Max Planck Society;

External Resource
No external resources are shared
Fulltext (public)

Kretschmer et al..pdf
(Publisher version), 2MB

Supplementary Material (public)
There is no public supplementary material available
Citation

Kretschmer, S., Ganzinger, K., Franquelim, H., & Schwille, P. (2019). Synthetic cell division via membrane-transforming molecular assemblies. BMC Biology, 17: 43. doi:10.1186/s12915-019-0665-1.


Cite as: http://hdl.handle.net/21.11116/0000-0006-9A52-0
Abstract
Reproduction, i.e. the ability to produce new individuals from a parent organism, is a hallmark of living matter. Even the simplest forms of reproduction require cell division: attempts to create a designer cell therefore should include a synthetic cell division machinery. In this review, we will illustrate how nature solves this task, describing membrane remodelling processes in general and focusing on bacterial cell division in particular. We discuss recent progress made in their in vitro reconstitution, identify open challenges, and suggest how purely synthetic building blocks could provide an additional and attractive route to creating artificial cell division machineries.