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Magnetic Resonance Fingerprinting with Chemical Exchange (MRF-X) for Quantification of Subvoxel T1, T2, Volume Fraction, and Exchange Rate

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Hamilton, J., Deshmane, A., Hougen, S., Griswold, M., & Seiberlich, N. (2015). Magnetic Resonance Fingerprinting with Chemical Exchange (MRF-X) for Quantification of Subvoxel T1, T2, Volume Fraction, and Exchange Rate. Poster presented at 23rd Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2015), Toronto, ON, Canada.


Cite as: https://hdl.handle.net/21.11116/0000-0006-9ACA-9
Abstract
A new technique termed MRF-X is introduced that models two-compartment chemical exchange to generate a dictionary for subvoxel mapping of T1, T2, volume fraction, and exchange rate. Simulations indicate that the MRF-X model can map subvoxel parameters in cases where standard mapping sequences would map a single effective T1 or T2 value. MRF-X has the potential to directly measure properties of tissue microstructure.