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Lesion-robust white-matter bundle identification through diffusion driven label fusion

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Gallardo,  Guillermo
Department Neuropsychology, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Anwander,  Alfred
Department Neuropsychology, MPI for Human Cognitive and Brain Sciences, Max Planck Society;

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Citation

Gallardo, G., Zanitti, G., Deslauriers-Gauthier, S., Higger, M., Bouix, S., Anwander, A., et al. (2020). Lesion-robust white-matter bundle identification through diffusion driven label fusion. Talk presented at 28th Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM). Virtual Conference. 2020-08-08 - 2020-08-14.


Cite as: http://hdl.handle.net/21.11116/0000-0006-D4B5-E
Abstract
White-matter pathologies disrupt the white-matter organization, that manifests as deficits in brain function. When treating such pathologies, it is of great importance to infer which pathways are affected. However, the white-matter lesions hamper the use of tractography to track fiber bundles. In this work, leveraging diffusion imaging, we propose a novel diffusion-driven technique to improve the localization of brain pathways. Aggregating information from few healthy subjects, our technique is able to localize both the affected pathways and the lesion interrupting when tracking is not possible.