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Towards clinical CEST-MRF: whole brain snapshot CEST MR Fingerprinting at 3T using spin-lock saturation and a centric 3D-EPI readout

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Herz,  K
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Mueller,  S
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Scheffler,  K
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Zaiss,  M
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Herz, K., Mueller, S., Perlman, O., Stirnberg, R., Stoecker, T., Scheffler, K., et al. (2020). Towards clinical CEST-MRF: whole brain snapshot CEST MR Fingerprinting at 3T using spin-lock saturation and a centric 3D-EPI readout. Poster presented at 2020 ISMRM & SMRT Virtual Conference & Exhibition.


Cite as: https://hdl.handle.net/21.11116/0000-0006-D863-7
Abstract
Quantitative CEST imaging is still not applied in clinical routine, as both quantification and whole brain coverage require usually long scan times. In this work, we present a CEST-MRF protocol using spin-lock saturation pulses and a fast 3D-EPI readout with whole brain coverage. This enables a fast generation of quantitative amide proton concentration maps of the entire brain at a clinical scanner.