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On the feasibility of a single scan B1+ correction scheme in combination with Multiple Interleaved Mode Saturation for quantitative CEST at 7 Tesla

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Zaiss,  M
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Liebert, S., Tkotz, K., Herrler, J., Liebig, P., Gumbrecht, R., Doerfler, A., et al. (2020). On the feasibility of a single scan B1+ correction scheme in combination with Multiple Interleaved Mode Saturation for quantitative CEST at 7 Tesla. Poster presented at 2020 ISMRM & SMRT Virtual Conference & Exhibition.


Cite as: http://hdl.handle.net/21.11116/0000-0006-D8A5-C
Abstract
In Chemical Exchange Saturation Transfer MR both B1+-inhomogeneity correction and mitigation have their limitations, in particular if large field-of views shall be covered. To overcome these limitations a Multiple Interleaved Mode Saturation scheme was applied together with a linear B1+ inhomogeneity correction method. Repeatability and reproducibility of the MTRRex metric for rNOE and APT were investigated. A combination of MIMOSA and a simple single point correction allows achieving repeatable and reproducible CEST contrast in whole brain with an acquisition time of 4min 54s.