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Poster

Investigation of a parallel transmission (pTx) GRE-readout with customized pulses for CEST MRI at 7 Tesla

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Zaiss,  M
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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https://www.ismrm.org/20/program_files/DP08-01.htm
(Abstract)

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Citation

Tkotz, K., Liebert, A., Herrler, J., Liebig, P., Dörfler, A., Uder, M., et al. (2020). Investigation of a parallel transmission (pTx) GRE-readout with customized pulses for CEST MRI at 7 Tesla. Poster presented at 2020 ISMRM & SMRT Virtual Conference & Exhibition.


Cite as: https://hdl.handle.net/21.11116/0000-0006-D8AB-6
Abstract
In Chemical Exchange Saturation Transfer MRI B1+-inhomogeneity influences both saturation and acquisition of the signal. Typically only a correction of the inhomogeneity of the CEST saturation is performed while the inhomogeneity of the readout is neglected. The influence of the readout was investigated in measurements using standard inhomogeneous 1Tx readout and a homogenized readout with customized pTx pulses. Compared to the 1Tx readout the readout with pTx pulses shows an increase of the homogeneity of the CEST contrast for CEST agents with low SNR like the amides and in regions with low 1Tx flip angle like the cerebellum.