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One Minute Whole-Brain Magnetization Transfer Ratio Imaging with Intrinsic B1-Correction

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Heule,  R
Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Afshari, R., Santini, F., Heule, R., Meyer, C., Pfeuffer, J., & Bieri, O. (2020). One Minute Whole-Brain Magnetization Transfer Ratio Imaging with Intrinsic B1-Correction. Poster presented at 2020 ISMRM & SMRT Virtual Conference & Exhibition.


Cite as: https://hdl.handle.net/21.11116/0000-0006-D8BC-3
Abstract
Magnetization transfer (MT), reflecting the exchange of magnetization between mobile and bound protons, has shown good potential for the diagnosis and prognosis of various neurological disorders, such as multiple sclerosis. Frequently, MT effects are assessed by measuring the contrast between two scans performed with and without saturation of the bound pool protons. Evidently, saturation is affected by B1 inhomogeneity and should be accounted for. In this work, we report on a very rapid one-minute whole-brain magnetization transfer ratio (MTR) imaging method offering intrinsic B1-correction.