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Quantification of 31P Human Brain spectra at 9.4T using ISIS and SPECIAL-semiLASER

MPS-Authors
/persons/resource/persons215104

Dorst,  J
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons215122

Ruhm,  L
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons133464

Avdievich,  N
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

/persons/resource/persons84402

Henning,  A
Research Group MR Spectroscopy and Ultra-High Field Methodology, Max Planck Institute for Biological Cybernetics, Max Planck Society;
Max Planck Institute for Biological Cybernetics, Max Planck Society;

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Citation

Dorst, J., Ruhm, L., Avdievich, N., Bogner, W., & Henning, A. (2020). Quantification of 31P Human Brain spectra at 9.4T using ISIS and SPECIAL-semiLASER. Poster presented at 2020 ISMRM & SMRT Virtual Conference & Exhibition.


Cite as: http://hdl.handle.net/21.11116/0000-0006-D8CF-E
Abstract
For phosphorus single voxel MR spectroscopy, ISIS is often the method of choice, but it requires an 8 steps encoding scheme and post-acquisition signal combination which makes it prone to motion. Therefore, a SPECIAL-semiLASER sequence for 31P MRS was implemented in this study, which only needs two encoding steps for 3D localization. Spectra from the human brain acquired at 9.4T with both sequences are compared in terms of absolute SNR and SNR efficiency. Absolute SNR as well as SNR efficiency is lower for SPECIAL-semiLASER, but calculated concentrations are comparable.