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Journal Article

MOSGA: Modular open-source genome annotator

MPS-Authors
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Hackl,  Thomas
Department of Biomolecular Mechanisms, Max Planck Institute for Medical Research, Max Planck Society;

/persons/resource/persons117949

Fischer,  Matthias G.
Department of Biomolecular Mechanisms, Max Planck Institute for Medical Research, Max Planck Society;

External Resource

https://arxiv.org/pdf/2009.03758
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https://arxiv.org/abs/2009.03758
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Citation

Martin, R., Hackl, T., Hattab, G., Fischer, M. G., & Heider, D. (2020). MOSGA: Modular open-source genome annotator. arXiv, 2009.03758, pp. 1-5.


Cite as: https://hdl.handle.net/21.11116/0000-0006-FED4-D
Abstract
The generation of high-quality assemblies, even for large eukaryotic
genomes, has become a routine task for many biologists thanks to recent
advances in sequencing technologies. However, the annotation of these
assemblies - a crucial step towards unlocking the biology of the organism of
interest - has remained a complex challenge that often requires advanced
bioinformatics expertise.
Here we present MOSGA, a genome annotation framework for
eukaryotic genomes with a user-friendly web-interface that generates and
integrates annotations from various tools. The aggregated results can be
analyzed with a fully integrated genome browser and are provided in a
format ready for submission to NCBI. MOSGA is built on a portable,
customizable, and easily extendible Snakemake backend, and thus, can be
tailored to a wide range of users and projects.
We provide MOSGA as a publicly free available web service at
https://mosga.mathematik.uni-marburg.de and as a docker container at
registry.gitlab.com/mosga/mosga:latest. Source code can be found at
https://gitlab.com/mosga/mosga