How DNA and RNA subunits might have formed to make the first genetic alphabet

Le Vay, Kristian; Mutschler, Hannes

doi:10.1038/d41586-020-01566-4

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How DNA and RNA subunits might have formed to make the first genetic alphabet

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Le Vay, Kristian
Mutschler, Hannes / Biomimetic Systems, Max Planck Institute of Biochemistry, Max Planck Society;

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Mutschler, Hannes
Mutschler, Hannes / Biomimetic Systems, Max Planck Institute of Biochemistry, Max Planck Society;

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Le Vay, K., & Mutschler, H. (2020). How DNA and RNA subunits might have formed to make the first genetic alphabet. Nature, 582(7810), 33-34. doi:10.1038/d41586-020-01566-4.

Cite as: https://hdl.handle.net/21.11116/0000-0007-190A-3

Abstract

Understanding the prebiotic origins of the nucleic acids is a long-standing challenge. The latest experiments support the idea that the first nucleic acid encoded information using a mixed 'alphabet' of RNA and DNA subunits.