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Journal Article

A novel sequence to improve auditory functional MRI with variable silent delays


Lee,  H. Sean
Department of Neuroscience, Max Planck Institute for Empirical Aesthetics, Max Planck Society;

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Shrestha, M., Lee, H. S., Nöth, U., & Deichmann, R. (2021). A novel sequence to improve auditory functional MRI with variable silent delays. Magnetic Resonance in Medicine, 85(2), 883-896. doi:10.1002/mrm.28479.

Cite as: https://hdl.handle.net/21.11116/0000-0007-2F02-3
Auditory functional MRI (fMRI) often uses silent inter‐volume delays for stimulus presentation. However, maintaining the steady‐state of the magnetization usually requires constant delays. Here, a novel acquisition scheme dubbed “pre‐Saturated EPI using Multiple delays in Steady‐state” (SEPIMS) is proposed, using spin saturation at a fixed delay before each volume to maintain steady‐state conditions, independent of previous spin history. This concept allows for variable inter‐volume delays and thus for flexible stimulus design in auditory fMRI. The purpose was to compare the signal stability of SEPIMS and conventional sparse EPI (CS‐EPI).