Kinetic Study of Disulfonimide-Catalyzed Cyanosilylation of Aldehydes by Using 
a Method of Progress Rates

Zhang, Zhipeng; Klussmann, Martin; List, Benjamin

doi:10.1055/s-0040-1707129

Item

ITEM ACTIONSEXPORT

Add to Basket

Local TagsRelease HistoryDetailsSummary

Released

Journal Article

Kinetic Study of Disulfonimide-Catalyzed Cyanosilylation of Aldehydes by Using a Method of Progress Rates

MPS-Authors

/persons/resource/persons58702

Klussmann, Martin
Research Group Klußmann, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

/persons/resource/persons58764

List, Benjamin
Research Department List, Max-Planck-Institut für Kohlenforschung, Max Planck Society;

External Resource

No external resources are shared

Fulltext (restricted access)

There are currently no full texts shared for your IP range.

Fulltext (public)

Zhang-Klussmann-List.pdf
(Publisher version), 2MB

Supplementary Material (public)

There is no public supplementary material available

Citation

Zhang, Z., Klussmann, M., & List, B. (2020). Kinetic Study of Disulfonimide-Catalyzed Cyanosilylation of Aldehydes by Using a Method of Progress Rates. Synlett, 31(16), 1593-1597. doi:10.1055/s-0040-1707129.

Cite as: https://hdl.handle.net/21.11116/0000-0007-43C1-3

Abstract

Kinetic study of organic reactions, especially multistep catalytic reactions, is crucial to in-depth understanding of reaction mechanisms. Here we report our kinetic study on the chiral disulfonimide-catalyzed cyanosilylation of an aldehyde, which revealed that two molecules of TMSCN are involved in the rate-determining C–C bond-forming step. In addition, the apparent activation energy, enthalpy of activation, and entropy of activation were deduced through a study of the temperature dependence of the reaction rates. More importantly, a novel and efficient method that makes use of the progress rates was developed to treat kinetic data obtained by continuous monitoring of the progress of a reaction by in situ FTIR.