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Journal Article

Smartphone‐based multimodal tethered capsule endoscopic platform for white‐light, narrow‐band, and fluorescence/autofluorescence imaging

MPS-Authors
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Sharma,  Gargi
Guck Division, Max Planck Institute for the Science of Light, Max Planck Society;

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Blessing,  Katharina
Singh Research Group, Research Groups, Max Planck Institute for the Science of Light, Max Planck Society;
Department of Physics, Friedrich- Alexander Universität Erlangen- Nürnberg;

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Gall,  Robert
Max Planck Institute for the Science of Light, Max Planck Society;

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Singh,  Kanwarpal
Max-Planck-Zentrum für Physik und Medizin, Max Planck Institute for the Science of Light, Max Planck Society;
Singh Research Group, Research Groups, Max Planck Institute for the Science of Light, Max Planck Society;
Department of Physics, Friedrich- Alexander Universität Erlangen- Nürnberg;

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jbio.202000324.pdf
(Preprint), 676KB

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Citation

Sharma, G., Thoma, O.-M., Blessing, K., Gall, R., Waldner, M., & Singh, K. (2020). Smartphone‐based multimodal tethered capsule endoscopic platform for white‐light, narrow‐band, and fluorescence/autofluorescence imaging. Journal of Biophotonics, e202000324. doi:10.1002/jbio.202000324.


Cite as: http://hdl.handle.net/21.11116/0000-0007-56B2-F
Abstract
Multimodal low‐cost endoscopy is highly desirable in poor resource settings such as in developing nations. In this work, we developed a smartphone‐based low‐cost, reusable tethered capsule endoscopic platform that allows white‐light, narrowband, and fluorescence/autofluorescence imaging of the esophagus. The ex‐vivo studies of swine esophagus were performed and compared with a commercial endoscope to test the white‐light imaging capabilities of the endoscope. The efficacy of the capsule for narrow‐band imaging was tested by imaging the vascularization of the tongue. To determine the autofluorescence/fluorescence capability of the endoscope, fluorescein dye with different concentrations was imaged. Furthermore, swine esophagus injected with fluorescein dye was imaged using the fluorescence/autofluorescence and the white‐light imaging modules, ex‐vivo. The overall cost of the capsules is approximately 12 €, 15 €, and 42 € for the white light imaging, the narrow‐band imaging, and the fluorescence/autofluorescence imaging respectively. In addition, the cost of the laser source module required for the narrow‐band imaging and the fluorescence/autofluorescence imaging is approximately 218 €. This device will open the possibility of imaging the esophagus in underprivileged areas.