Switching first contact: photocontrol of E. coli adhesion to human cells

Möckl, Leonhard; Mueller, A.; Braeuchle, C.; Lindhorst, T. K.

doi:10.1039/c5cc08884d

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Switching first contact: photocontrol of E. coli adhesion to human cells

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Möckl, L., Mueller, A., Braeuchle, C., & Lindhorst, T. K. (2016). Switching first contact: photocontrol of E. coli adhesion to human cells. Chemical Communications, 52(6), 1254-1257. doi:10.1039/c5cc08884d.

Cite as: https://hdl.handle.net/21.11116/0000-0007-6989-9

Abstract

We have shown previously that carbohydrate-specific bacterial adhesion to a non-physiological surface can be photocontrolled by reversible E/Z isomerisation using azobenzene-functionalised sugars. Here, this approach is applied to the surface of human cells. We show not only that bacterial adhesion to the azobenzene glycoside-modified cell surface is higher in the E than in the Z state, but add data about the specific modulation of the effect.