English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT

Released

Journal Article

Super-resolution Microscopy with Single Molecules in Biology and Beyond–Essentials, Current Trends, and Future Challenges

MPS-Authors
There are no MPG-Authors available
External Ressource
No external resources are shared
Fulltext (public)

jacs.0c08178.pdf
(Publisher version), 5MB

Supplementary Material (public)
There is no public supplementary material available
Citation

Möckl, L., & Moerner, W. E. (2020). Super-resolution Microscopy with Single Molecules in Biology and Beyond–Essentials, Current Trends, and Future Challenges. Journal of the American Chemical Society, 142(42), 17828-17844. doi:10.1021/jacs.0c08178.


Cite as: http://hdl.handle.net/21.11116/0000-0007-6A50-8
Abstract
Single-molecule super-resolution microscopy has developed from a specialized technique into one of the most versatile and powerful imaging methods of the nanoscale over the past two decades. In this perspective, we provide a brief overview of the historical development of the field, the fundamental concepts, the methodology required to obtain maximum quantitative information, and the current state of the art. Then, we will discuss emerging perspectives and areas where innovation and further improvement are needed. Despite the tremendous progress, the full potential of single-molecule super-resolution microscopy is yet to be realized, which will be enabled by the research ahead of us.