From pyrazolones to azaindoles : evolution of active-site SHP2 inhibitors based 
on scaffold hopping and bioisosteric replacement

Mostinski, Yelena; Heynen, Guus J. J. E.; López-Alberca, Maria Pascual; Paul, Jerome; Miksche, Sandra; Radetzki, Silke; Schaller, David; Shanina, Elena; Seyffarth, Carola; Kolomeets, Yuliya; Ziebart, Nandor; de Schryver, Judith; Oestreich, Sylvia; Neuenschwander, Martin; Roske, Yvette; Heinemann, Udo; Rademacher, Christoph; Volkamer, Andrea; von Kries, Jens Peter; Birchmeier, Walter; Nazaré, Marc

doi:10.1021/acs.jmedchem.0c01265

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From pyrazolones to azaindoles : evolution of active-site SHP2 inhibitors based on scaffold hopping and bioisosteric replacement

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Shanina, Elena
Christoph Rademacher, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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Rademacher, Christoph
Christoph Rademacher, Biomolekulare Systeme, Max Planck Institute of Colloids and Interfaces, Max Planck Society;

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Mostinski, Y., Heynen, G. J. J. E., López-Alberca, M. P., Paul, J., Miksche, S., Radetzki, S., et al. (2020). From pyrazolones to azaindoles: evolution of active-site SHP2 inhibitors based on scaffold hopping and bioisosteric replacement. Journal of Medicinal Chemistry, 63(23), 14780-14804. doi:10.1021/acs.jmedchem.0c01265.

Cite as: https://hdl.handle.net/21.11116/0000-0007-7565-4

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